This report describes the global market size of HLA Typing from 2019 to 2022 and its CAGR from 2019 to 2023, and also forecasts its market size to the end of 2031 and its expected to grow with a CAGR of 36.4% from 2024 to 2031.
Due to the COVID-19 pandemic, the global market for HLA Typing estimated at US 33.4 $ billion in the year 2023, is projected to reach a revised size of US 562.97$ million by 2031, growing at a CAGR of 36.4% during the forecast period 2024-2031.
HLA typing is a laboratory test used to identify specific human leukocyte antigen (HLA) markers on an individual's cells. These markers play a crucial role in the immune system's ability to distinguish between self and non-self, making HLA typing essential for organ transplantation and autoimmune disease diagnosis. By matching HLA types between donors and recipients, healthcare providers can reduce the risk of transplant rejection. The test is also used in research and personalized medicine to understand genetic predispositions to various diseases. Accurate HLA typing helps in ensuring compatibility and improving patient outcomes in medical treatments.
For geography segment, regional supply, demand, major players, price is presented from 2019 to 2031. This report cover following regions:
North America
Asia-Pacific
Europe
Middle East and Africa
South America
The key countries for each regions are also included such as United States, China, Japan, India, Korea, ASEAN, Germany, France, UK, Italy, Spain, CIS, and Brazil etc.
For competitor segment, the report include global key players of HLA Typing as well as some small players. The information for each competitor include:
Company Profile
Main Business Information
SWOT Analysis
Sales Volume, Revenue, Price and Gross Margin
Market Share
By Technology
Molecular Assays
Polymerase Chain Reaction (PCR)
Sequence-Specific Oligonucleotide (SSO) Probes
Sequence-Specific Primer (SSP) Typing
Real-Time PCR (qPCR)
Next-Generation Sequencing (NGS)
Sanger Sequencing
Non-Molecular Assays
Serological Assays
Mixed Lymphocyte Culture (MLC)
HLA typing utilizes various technologies to accurately determine specific human leukocyte antigen markers, each offering distinct advantages. Molecular assays include Polymerase Chain Reaction (PCR) techniques such as Sequence-Specific Oligonucleotide (SSO) Probes and Sequence-Specific Primer (SSP) Typing, which are used to amplify and identify specific HLA alleles with high precision. Real-Time PCR (qPCR) enhances this by providing quantitative data on allele expression. Next-Generation Sequencing (NGS) offers a comprehensive approach by sequencing entire HLA genes, allowing for high-resolution typing and the identification of novel alleles. Sanger Sequencing provides accurate sequence data for individual HLA genes, often used in conjunction with other methods for confirmation. Non-molecular assays include Serological Assays, which detect HLA antigens using antibody-based techniques, and Mixed Lymphocyte Culture (MLC), which assesses compatibility based on the response of lymphocytes to each other. These non-molecular methods are less commonly used today but can still provide valuable information in specific contexts. Together, these technologies ensure precise and reliable HLA typing, critical for successful transplantation and disease management.
Product & Service
Instruments
Sequencers
PCR Systems
Reagents & Consumables
Oligonucleotide Probes
Antibodies
Other Assay Kits
Software & Services
HLA Typing Software
Data Analysis Services
Consulting Services
HLA typing involves a range of products and services designed to facilitate accurate and efficient identification of human leukocyte antigen markers. Instruments are crucial for conducting HLA typing and include Sequencers, which provide detailed sequencing data for high-resolution typing, and PCR Systems, which amplify specific DNA regions to detect HLA alleles. Reagents & Consumables support these instruments and include Oligonucleotide Probes for detecting specific HLA sequences, Antibodies for serological assays, and Other Assay Kits for various molecular and non-molecular typing methods. Software & Services enhance the utility of these products by offering HLA Typing Software for processing and interpreting complex genetic data, Data Analysis Services to provide detailed insights and validation, and Consulting Services for expert guidance on optimizing typing protocols and addressing specific research or clinical needs. Together, these products and services ensure comprehensive support for accurate HLA typing and its applications in transplantation and disease management.
Application
Transplantation:
Solid Organ Transplantation:
Kidney
Liver
Heart
Hematopoietic Stem Cell Transplantation (HSCT)
Disease Diagnosis
Cancer
Autoimmune Diseases
Infectious Diseases
HLA typing plays a critical role in various medical applications, primarily in transplantation and disease diagnosis. In solid organ transplantation, accurate HLA matching is essential to minimize the risk of organ rejection and improve patient outcomes. For kidney, liver, and heart transplants, HLA typing helps ensure compatibility between the donor and recipient, reducing the likelihood of graft-versus-host disease and enhancing the success of the transplant. In hematopoietic stem cell transplantation (HSCT), HLA typing is equally crucial. It helps identify suitable donors for bone marrow or peripheral blood stem cell transplants, which are used to treat conditions such as leukemia and lymphoma. Proper HLA matching improves the chances of graft acceptance and reduces complications related to immune responses. Beyond transplantation, HLA typing is used in disease diagnosis. In cancer, it aids in identifying specific genetic markers associated with various malignancies, helping in diagnosis and treatment planning. For autoimmune diseases, HLA typing can reveal genetic predispositions and assist in understanding the underlying mechanisms of disorders such as rheumatoid arthritis or lupus. Additionally, in infectious diseases, HLA typing helps in understanding how genetic variations affect individual responses to infections and vaccines. Overall, HLA typing is a versatile tool with significant implications for both therapeutic and diagnostic applications.
Research
Immunogenetics
Population Genetics
HLA typing is a key tool in research fields such as immunogenetics and population genetics. In immunogenetics, HLA typing is used to explore the relationship between genetic variations in HLA genes and immune system function. This research helps in understanding how different HLA types influence susceptibility to autoimmune diseases, response to infections, and effectiveness of immunotherapies. In population genetics, HLA typing helps in studying genetic diversity and allele frequency within different populations. This research provides insights into human migration patterns, evolutionary history, and the genetic basis of disease prevalence across diverse groups. By analyzing HLA data from various populations, researchers can identify genetic markers associated with diseases and better understand the genetic factors contributing to health disparities. Overall, HLA typing enhances our understanding of genetic influences on immunity and disease across populations.
End User
Hospitals & Transplant Centers
Academic & Research Institutes
Diagnostic Laboratories
Pharmaceutical & Biotechnology Companies
HLA typing is utilized by a range of end users in the medical and research fields. Hospitals & transplant centers are primary users, relying on HLA typing to ensure compatibility in organ and stem cell transplants, thereby reducing the risk of rejection and improving patient outcomes. Academic & research institutes use HLA typing to investigate genetic factors related to immunology, autoimmune diseases, and cancer, contributing to advancements in medical science and personalized medicine. Diagnostic laboratories employ HLA typing to provide crucial genetic information for disease diagnosis, especially for conditions requiring precise genetic matching. These laboratories offer testing services for both clinical and research purposes, ensuring accurate identification of HLA types. Pharmaceutical & biotechnology companies use HLA typing to develop and test new drugs and therapies, particularly those targeting specific genetic markers or tailored to individual genetic profiles. This diverse usage underscores HLA typing's importance in enhancing medical treatments, advancing research, and improving diagnostic accuracy across various fields.
Key Players
Thermo Fisher Scientific Inc.
Bio-Rad Laboratories Inc.
Qiagen N.V.
Omixon Inc.
GenDx.
Illumina Inc.
TBG Diagnostics Limited.
Dickinson and Company.
Takara Bio Inc.
F. Hoffman-La Roche Limited.
Pacific Biosciences
Please ask for sample pages for full companies list
Base Year: 2023
Historical Data: from 2019 to 2023
Forecast Data: from 2024 to 2031
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